Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0456217
PubChem CID
Molecular Formula
C69H114N30O17S4
Molecular Weight
1764.132 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
XFBDKMSGGGCNAI-WVHVKVEVSA-N
InChI
InChI=1S/C69H114N30O17S4/c1-32(2)19-41-58(108)95-45(52(71)102)26-117-119-28-47-63(113)94-44(25-100)6...
IUPAC Name
(1R,6R,9S,12S,15S,18S,21S,24S,27S,30R,33S,36S,42S,45S,50R)-50-[(2-aminoacetyl)amino]-15,21,27-tris(3-carbamimidamidopropyl)-45-(hydroxymethyl)-18,42-bis(1H-imidazol-5-ylmethyl)-12,24-dimethyl-9-(2-methylpropyl)-8,11,14,17,20,23,26,29,32,35,41,44,47,49-tetradecaoxo-33-propan-2-yl-3,4,52,53-tetrathia-7,10,13,16,19,22,25,28,31,34,40,43,46,48-tetradecazatricyclo[28.17.7.036,40]tetrapentacontane-6-carboxamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

120124 0 0 0 0 0 0 0 0999 V2000
5.4151 -12.9387 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.7878 -11.5762 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.2941 -11...

Experimental Data

Activity Data

Target Ion Channel
Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 3.1 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
not mention
Holding Potential
not mention mV
Temperature
not mention
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
120
Rotatable Bonds
23
logP
-9.5458
Complexity
444.6082
TPSA (Ų)
760.11
H-Bond Donors
28
H-Bond Acceptors
27
Ring Count
5
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